Roche 1 Estimated H-index: 1. Estimated H-index: 1. Find in Lib. Add to Collection. A year-old girl presented with painful, erythematous gingivae, which occasionally developed blisters.

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Roche 1 Estimated H-index: 1. Estimated H-index: 1. Find in Lib. Add to Collection. A year-old girl presented with painful, erythematous gingivae, which occasionally developed blisters. There were no other mucosal or skin lesions. Clinical, histopathological and immunofluorescence studies suggested a diagnosis of benign mucous membrane cicatricial pemphigoid, presenting as desquamative gingivitis.

Benign mucous membrane pemphigoid in childhood is rare and only a few cases with exclusive oral mucosal involvement have been reported in the literature. The desquamative gingivitis responded well to a topical steroid regimen. Pemphigus membraneux muqueux benin avec gingivite desquamative chez un enfant de 14 ans Le cas presente est celui d'une jeune fille de 14 ans avec gingivite erythemateuse, douloureuse et bulles occasionnelles.

Il n'y avait pas d'autres lesions de la peau ou de la muqueuse. Les recherches cliniques, histo-pathologiques et en immunofluorescence etaient en faveur d'un pemphigus benin cicatriciel de la membrane muqueuse, se presentant comme une gingivite desquamative. Le pemphigus membraneux muqueux dans l'enfance est rare et seulement quelques cas, avec participation de la muqueuse orale, ont ete decrits dans la litterature.

La gingivite desquamative repond bien a un traitement topique steroidien. Ein gutartiges Mukoses Membran-Pemphigoid welches sich als ein desquamatose Gingivitis presentierte, bei einen 14 Jahr alten Kind Ein 14 Jahr altes Madchen erscheint mit einer schmerzvollen geroteten Gingiva mit heufiger Blasenbildung.

Keinerlei andere mukose oder Hautlasionen waren zu finden. Klinische histopathologische und immunfluoreszierende Untersuche fuhrten zur Diagnose eines gutartigen mukosen Membran-Pemphigoid im der Form einer desquamatosen Gingivitis.

Solche Pemphigoide sind selten in der Kindheit, und es wurde nur, uber wenige Falle welche exklusiv die orale Mukosa befallen, in der Literatur berichtet. Diese Form der Gingivitis reagiert sehr gut auf der Oberflachean-wendung von Steroiden. Penfigo membranoso mucoso benigno presentadose como gingivitis descamativa en una nina de 14 anos de edad Una nina de 14 anos de edad se presentO con encia eritematosa y con dolor.

Ocasionalmente se presentaban vesiculas. No hubo ninguna otra lesiOn en la mucosa o piel. Los examenes clinicos, histopatolOgicos y de immunofluorescencia sugirieron un diagnOstico de penfigo membranoso cicatricial mucoso benigno presentandose como gingivitis descamativa.

Esta lesiOn es muy rara en ninos y solo algumos casos han sido reportados en la literatura. La gingivitis descamativa respondiO favorablemente a la terapia con esteroides tOpicos. References 15 Citations 11 Cite. Childhood cicatricial pemphigoid with exclusive gingival involvement. Read Later. Gingival manifestations of childhood cicatricial pemphigoid. Benign mucous membrane pemphigoid in an year-old woman.

After signing in, all features are FREE. References Mucous membrane pemphigoid. Thomas P. Mucous membrane pemphigoid MMP is a chronic, subepithelial autoimmune disease, which predominantly involves mucosal surfaces and results in mucosal blistering, ulceration, and subsequent scarring.

The condition belongs to a group of mucocutaneous autoimmune blistering disorders often collectively referred to as subepithelial bullous dermatoses SEBDs.

Clinical, historic, and therapeutic features of cicatricial pemphigoid: A literature review and open therapeutic trial with corticosteroids. Karen A. Abstract Cicatricial pemphigoid is at present an incurable, autoimmune disease that involves mucosa and skin.

We have documented the clinical, microscopic, and therapeutic features of 23 patients with cicatricial pemphigoid and added these to reports of past literature. The mean age at the time of diagnosis was 63 years, and women were involved twice as often as men. Treatment experience at two institutions. Abstract The initial oral findings and treatment in 50 cases of mucous membrane pemphigoid are presented.

Histologic and immunologic studies were undertaken in each case to confirm the clinical diagnosis. The treatments prescribed are summarized and illustrate that topical steroids are effective, but in some cases systemic steroid therapy with or without other immunologically active drugs is required.

A significant number of patients had extraoral manifestations of the disorder. Steroids and growth. Cicatricial pemphigoid. A case of onset at age 5. Cicatricial pemphigoid is a chronic subepideimal bullous dermatosis which primarily involves the mucous membranes. It is a disease found almost exclusively among middleaged and elderly persons. This report describes a case of cicatricial pemphigoid with onset at age 5 and involving primarily the mucous membranes of the mouth and eyes.

The patient cleared well on 40 mg of Prednisone and has been maintained on a regimen of 7. We report a 6-year-old male who had erosions of the oral and genital mucosa, conjunctivitis, hoarseness, dysphagia, recurrent vomiting, and weight loss. Upper airway obstruction due to a chronically inflamed and scarred epiglottis necessitated tracheostomy. Biopsy of tissue from a solitary cutaneous lesion demonstrated a subepidennal bulla.

Direct and indirect immunofluorescence confirmed a d Treatment of cicatricial benign mucous membrane pemphigoid with dapsone. Rogers Mayo Clinic H-Index: Seehafer Mayo Clinic H-Index: 2.

Harold O. Perry Mayo Clinic H-Index: Treatment of cicatricial pemphigoid is a problem because patients afflicted are elderly, the disease is chronic, systemic agents required for control are potentially toxic particularly to older patients , and the disease is often in an advanced stage when the diagnosis is established and requires aggressive therapy for control.

We selected dapsone as an alternative anti-inflammatory agent because it had provided control in a subset of patients with bullous pemphigoid, five of six who had oral l Cited By Pemphigoid, Benign Mucosal. Pemphigus, Pemphigoid and Epidermolysis Bullosa Acquisita. Jonkman H-Index: Mohamed Ridha Kamoun H-Index: We describe a new case in a month-old boy, who is to our knowledge the youngest patient reported yet.

The disorder had begun 10 months before he was referred to our department by mucosal crusted erosions of the oral and nasal cavities and conjunctivae.

Cutaneous examination showed buccal erosions with limited mouth opening, entropion of the lower eyeli Oral mucous membrane pemphigoid in a 6-year-old boy: diagnosis, treatment and 4 years follow-up. Mostafa H-Index: 1. Hassib H-Index: 1. Amany H. Nemat H-Index: 1. Childhood oral pemphigoid is extremely rare and usually takes the form of desquamative gingivitis.

Case report. We describe a 6-year-old boy who presented with gingival bleeding, pain, eating difficulty, and peeling of the gums. Clinical examination revealed desquamative gingivitis with no extra-oral involvement.

The diagnosis was established as oral pemphigoid based on the clinical, histological, and immunofluorescence findings. Symptoms resolved on treatment with occlusive topical The term desquamative gingivitis DG refers to a clinical manifestation that can be caused by several disorders. Many of them are immunologically mediated; in addition to the oral cavity, they can affect extraoral mucocutaneous sites, e.

The degree of oral, periodontal, and systemic involvement determines the overall morbidity and, sometimes, the mortality of these disorders. We comprehensively review disorders commonly Obravnava bolnikov z deskvamacijskim gingivitisom Treatement of patients with desquamative gingivitis. Desquamative gingivitis DG is a chronic gingival inflammation that is manifested clinically by erythema, epithelial desquamation, erosion, ulceration, and occasionally the presence of vesiculobullous lesions.

DG is not caused by bacterial plaque. It is most commonly a manifestation of immunologically mediated disorders, such as oral lichen planus, pemphigoid or pemphigus vulgaris. DG is a relatively rare condition that affects adults after the age of 50 and is more prevalent in females. It can Childhood oral mucous membrane pemphigoid presenting as desquamative gingivitis in a 4-year-old girl.

Mucous membrane pemphigoid is a chronic inflamma tory, bullous subepithelial auto-immune disease, with predominant involvement of the mucosal surfaces. Oral mucous membrane pemphigoid occurring in childhood is extremely rare. We describe a new case of this entity occurring in a 4-year-old girl who presented with desquamative gingivitis.

Diagnosis was based on clinical presentation, histopathology, immunofluorescence and immunoblotting examinations. Treatment and 2-year.


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The aim of this report is to diagnose the cause for episodic, shifting type of mild inflammation in the isolated areas of gingiva noted by the patient for 1 year. A year-old female patient presented with a chief complaint of mild pain and occasional burning sensation confined to the gingiva to the Department of Periodontology and Oral Implantology. Clinical presentation of the gingiva was seen to mimic mild form of gingivitis for 1 year, with no noted systemic involvement gingival biopsy was performed. The presence of Tzanck cell was noted along with intraepithelial split pointing toward pemphigus. Thus, the study concludes that thorough and meticulous gingival examination can reveal the picture of underlying systemic alterations and is the key for early diagnosis and prompt treatment.


Benign mucous membrane pemphigoid presenting as desquamative gingivitis in a 14‐year‐old child

Desquamative gingivitis is an erythematous red , desquamatous shedding and ulcerated appearance of the gums. Desquamative gingivitis involves lesions of the free and attached gingiva. Unlike plaque -induced inflammation of the gums normal marginal gingivitis , desquamative gingivitis extends beyond the marginal gingiva, involving the full width of the gingiva and sometimes the alveolar mucosa. Caused by various autoimmune diseases as well as allergies. Erosive lichen planus, mucous membrane pemphigoid , pemphigus vulgaris, erythema exsudativum multiforme and lupus erythematosus.

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