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Drugs and chirality: a brief overview. Vera Lucia Eifler Lima. Ipiranga - - Porto Alegre - RS. The concepts of stereochemistry and chirality are introduced, and the ability to distinguish among the different receptors caused by one stereoselective action against chiral drugs is presented. The importance of the behaviour of chiral drugs is emphasized. Keywords: chirality; chiral drugs; pharmaceutics.
Antes de abordarmos os aspectos que envolvem o termo "quiralidade", torna-se importante o situarmos num contexto mais amplo de "isomeria". Para os alquenos, na maioria da vezes, pode-se igualmente falar em Z e E para cis e trans, respectivamente. A warfarina 4 inclui-se nesta categoria. Deutsch, D. Surakitbanharn, Y. Millership, J. Eliel, E. Carey, F. New York, Mc Graw-Hill, Madesclaire, M.
Section E. Fundamental Stereochemistry. Thall, E. Hyneck, M. Chirality: Pharmacological Action and Drug Development. BROWN ed. Londres, Academic Press, Silverman, R;. San Diego, Academic Press, Fassihi, A. Patrick, G. An Introduction to Medicinal Chemistry. Oxford, Oxford University Press, Eifler Lima, V. Casy, A. Chirality , 4 , Carr, G.
Paris, Masson, Gao, Y. Wainer, I. New York, Marcel Dekker, Zhang, M. Towart, R. Knabe, J. Hutt, A. Jeffrey, P. Cerletti, C. Caldwell, J. News , 2, Ariens, E. Brown ed. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.
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