AUTOSENSITIZATION DERMATITIS PDF

THE CONCEPT of autosensitization, whereby a person becomes sensitized in one or more of his organs to a substance elaborated from his own tissue proteins, has been a stimulating subject for investigation in the past decade. Whitfield 1 was probably the first to apply this concept to the field of dermatology. In , he reported the cases of two patients in whom generalized toxic eruptions appeared approximately 10 days after the occurrence of traumatic hematomas. A generalized papular, urticarial eruption developed in a third patient 11 days after the acute exacerbation of a dermatitis of the legs. In another patient, a red-streaked urticaria wheal developed whenever serum from a vesiculobullous eczema of the legs came in contact with normal areas of the skin.

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THE CONCEPT of autosensitization, whereby a person becomes sensitized in one or more of his organs to a substance elaborated from his own tissue proteins, has been a stimulating subject for investigation in the past decade.

Whitfield 1 was probably the first to apply this concept to the field of dermatology. In , he reported the cases of two patients in whom generalized toxic eruptions appeared approximately 10 days after the occurrence of traumatic hematomas. A generalized papular, urticarial eruption developed in a third patient 11 days after the acute exacerbation of a dermatitis of the legs.

In another patient, a red-streaked urticaria wheal developed whenever serum from a vesiculobullous eczema of the legs came in contact with normal areas of the skin.

In , Dennie, McBride, and Davis 2 noted the occurrence of a generalized exfoliative dermatitis. Coronavirus Resource Center. All Rights Reserved. Twitter Facebook Email. This Issue. Save Preferences. Privacy Policy Terms of Use. Sign in to access your subscriptions Sign in to your personal account. Institutional sign in: OpenAthens Shibboleth. Create a free personal account to download free article PDFs, sign up for alerts, and more.

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Autosensitization Dermatitis - How Can it Be Treated?

If your institution subscribes to this resource, and you don't have a MyAccess Profile, please contact your library's reference desk for information on how to gain access to this resource from off-campus. Autosensitization dermatitis refers to a phenomenon in which an acute dermatitis develops at cutaneous sites distant from an inflammatory focus, and where the secondary acute dermatitis is not explained by the inciting cause of the primary inflammation. The term autosensitization dermatitis was coined in by Whitfield to describe reaction patterns ranging from a generalized, erythematous, morbilliform, and urticarial eruption after blunt trauma to a generalized, petechial, papulovesicular dermatitis after the acute irritation of chronic stasis dermatitis. Other precipitating factors for autosensitization have included the application of irritant or sensitizing chemicals, 14 ionizing radiation, 15 , 16 and retained suture material. Although the disease was originally thought to be due to autosensitization to epidermal antigens, 11 this concept has not been experimentally verified.

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Autosensitization dermatitis: A case of rosacea-like id reaction

Autosensitization dermatitis, or id reaction, is a cutaneous phenomenon in which an acute secondary dermatitis develops at a location distant from a primary inflammatory focus. However, multiple infectious organisms including bacteria, viruses, parasites, and fungi are found to cause reactions at areas distant to the site of infection. Id reactions do not always present as eczematous eruptions and may be urticarial, lichenoid, morbilliform, psoriatic, or scarlatiniform in morphology. Additionally, erythema nodosum and erythema multiforme have been observed, among other cutaneous responses.

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AUTOSENSITIZATION DERMATITIS Discussion and Protocol of an Experiment

The skin is susceptible to a wide range of ailments and conditions, since it is the most exposed part of the body. Autoeczematisation generally known as autosensitization dermatitis is skin inflammation caused by bacteria, which are present in various parts of the human body. The eczema or infection usually begins from the arms and legs before spreading to the rest of the body. It is also referred to as id response. It is an intense response to a variety of stimuli that affect the skin.

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