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Acquired autoimmune hypothyroidism is rare in early childhood, however, it must be considered in a 4 year old child with medical his-tory of delayed growth, increased somnolence, difficulty concentrating, and reduced activity. We report on the case of full clinical picture of severe hypothyroidism in one of the twins. Thyroid function deteriorated in one of the sisters, resulting in mental, motor and growth slowdown, remaining undiagnosed for about 2 years, while the other sister developed normally. In the reported case, severe hypothy-roidism and growth deficiency were accompanied by celiac disease. Initiation of L-thyroxine therapy resulted in an immediate response that increased the growth velocity by more than 2.

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Acquired autoimmune hypothyroidism is rare in early childhood, however, it must be considered in a 4 year old child with medical his-tory of delayed growth, increased somnolence, difficulty concentrating, and reduced activity. We report on the case of full clinical picture of severe hypothyroidism in one of the twins. Thyroid function deteriorated in one of the sisters, resulting in mental, motor and growth slowdown, remaining undiagnosed for about 2 years, while the other sister developed normally.

In the reported case, severe hypothy-roidism and growth deficiency were accompanied by celiac disease. Initiation of L-thyroxine therapy resulted in an immediate response that increased the growth velocity by more than 2. This confirms the dominant role of thyroid hormones over celiac disease in the growth process, as the catch up effect started before gluten free diet was introduced.

Keywords: children; growth deficiency; hypothyroidism. This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. Search: Search. Advanced Clipboard. Create file Cancel. Email citation To:. Format: Summary Summary text Abstract Abstract text.

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Abstract in English , Polish. Similar articles A case with atrophic autoimmune thyroiditis-related hypothyroidism causing multisystem involvement in early childhood.

Kurnaz E, et al. Turk J Pediatr. PMID: Rare cases of autoimmune hypothyroidism in young children. Tronconi GM, et al. J Pediatr Endocrinol Metab. Very early onset of autoimmune thyroiditis in a toddler with severe hypothyroidism presentation: a case report.

Marzuillo P, et al. Ital J Pediatr. Feldkamp J. Dtsch Med Wochenschr. Epub Nov PMID: Review. Orv Hetil. Show more similar articles See all similar articles. Publication types Case Reports Actions. Diet, Gluten-Free Actions. Female Actions. Humans Actions. Twins Actions. Substances Thyroxine Actions. Supplementary concepts Hypothyroidism, Autoimmune Actions.

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Pomeranian Journal of Life Sciences

Celiac disease is a frequent disease of the alimentary tract in children. Clinical presentation of the disease is variable and depends on type of the disease. The aim of the study was an analysis of clinical findings, selected laboratory features and coexisting diseases in children and adolescents with celiac disease. Material and Methods.

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